By John O’Neill (John is the managing director of Advance Nutrition.
With his many years of practical experience with the testing of numerous brands of Coenzyme Q10 both local and overseas, he may be regarded as the world’s foremost authority on CoQ10 brand testing.
He is the author of a highly revealing book on energy production, ‘Breaking the Sound Barrier of Human Energy Potential’. Through his book, John is trying to tell all fitness aspirants, athletes, bodybuilders and other health enthusiasts, the safe and yet effective way of attaining their goal in the fitness arena without the danger of long-term permanent bodily injury.)
Seventeen years spent testing about 100 different Coenzyme Q10 (Ubiquinone, Ubidecaronene) formulations, attempting to improve absorption, delivery and efficiency of Coenzyme Q10 into the aerobic energy systems within human cells (mitochondria) has been my overwhelming “passion of life.”
Good fermented (natural) CoQ10 powder, along with careful laboratory handling should in dry capsule form deliver immediate (one minute) results in short- term tested efficiency. It should also give on going subtle health improvements year after year. This fact is known to me because one has documented consistent personal physical improvements in endurance and strength since including quality produced Coenzyme Q10 in my diet over the last 11 years, a complete change from the downward spiralling direction previously.
I’ve been involved personally with approximately 30,000 aerobic human efficiency tests on the subject of Coenzyme Q10 alone in the last 17 years entailing a broad spectrum of 91 different worldwide brands of CoQ10 using them as a comparison standard with our own locally (Australian) produced product. Some of these brands were tested 40 times to ascertain accuracy.
Facts that emerged during testing showed that soft gel, oil-based delivery CoQ10 formulations do exhibit increased blood plasma levels of CoQ10. However, it also showed high urine excretion rates of CoQ10! The CoQ10 delivery system that we use (phosphate-based) does not show high levels of CoQ10 excretion in urine even after massive doses are administered.
The system we use is far superior because it (CoQ10) is absorbed within seconds into surrounding arteries and muscles.
It does not keep circulating in the blood, and to kidneys which automatically recognize the fact that it (CoQ10) is far above normal levels and is therefore excreted in the urine.
Coenzyme Q10 belongs, stores and is used by cellular mitochondria (aerobic system of cells). The quicker it is delivered to mitochondrial sites. the less is lost. and increased efficiency is gained.
We have tested 26 soft gel oil-based delivery CoQl0 with unbiased arbitrators overseeing testing procedures. Most of these soft get oil-based delivery preparations did produce some varying physical improvement efficiencies. The best was an American life extension formula which consistently gave 30% increase in efficiency only, according to milligrams of CoQ10 used compared with our local (Australian) product over a week long test. Some brands delivered zero efficiency readings even when subjects were given 225 – 450 milligrams of CoQ10 per day.
Modern pharmacology at this point in time worldwide demands blood plasma level of CoQ10 as evidence of cellular delivery. But in our experience, oils and fats drastically inhibit the amount of CoQ10 that can be absorbed through mitochondrial membranes where it is essentially used for efficient aerobic energy production. The fact is evident by treadmill and ergometer testing in human subjects conducted by myself in the presence of impartial judges. During the last 17 years, modern medicine can detect most essential nutrients in our blood plasma and generally that is a guide indicating cellular absorption of nutrients. But this is not always the truth.
There is only one real test that is foolproof in terms of body cell nutrient absorption and consequent physical improvements. This occurs when subjects are subjected to work-rate, heart-rate evaluations under physical load. With top quality CoQ10. 98% of people will show increased efficiencies under workload once CoQ10 is administered. The remaining 2% will generally respond within one week. Never have I recorded one case history with any subject using our CoQ10 where there has been no improvement given time. This statement is made with the aid of 30,000 separate stress tests concerning CoQ10 research.
Unfortunately, modern medicine has not yet managed to see or understand exactly what occurs within the mitochondria in respect to behaviour of the atoms of 84 elements that we use in our cells to create energy in the quest for survival.
Even our best microscopes would have to improve their magnification capacity by some 15 times to see an atom of hydrogen at work in the mitochondria.
The movement of hydrogen and oxygen atoms within the mitochondria is the major factor contributing to low toxic aerobic energy production necessary for health and survival.
Good quality CoQ10 contains a massive molecular structure of active hydrogen. It is my humble learning experience that the hype surrounding soft gel, oil-based delivery of CoQ10 does not stand up when faced with the human physical testing evidence with either short term or long term in terms of CoQ10 potentials. If it did, I would use oil-based delivery formula.
It is yet another case of “Let The Buyer Beware!”
The quality of Coenzyme Q10 varies greatly from supplier to supplier so select carefully.
By John O’Neill ©